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Mounjaro FDA Approval For Weight Loss

Created by Naira Abd Elwahed in 18 May 2025
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Mounjaro FDA Approval For Weight Loss


The U.S. Food and Drug Administration (FDA) has approved Mounjaro (tirzepatide), initially developed for type 2 diabetes, as a highly effective weight loss medication. This approval marks a significant advancement in obesity treatment, offering new hope for individuals struggling with weight management. 

In this article from TebZone the CME Platform we clear all doubts about using Mounjaro For Weight Loss.

What is Mounjaro?

Mounjaro, developed by Eli Lilly, is a dual GIP and GLP-1 receptor agonist. These hormones regulate blood sugar and appetite, making the drug effective not only for diabetes but also for substantial weight loss.

FDA Approval for Weight Loss

While Mounjaro was first approved in May 2022 for type 2 diabetes, its remarkable weight loss effects led to further studies.

Clinical trials demonstrated that participants lost up to 20-25% of their body weight, surpassing the results of other weight loss medications like Ozempic and Wegovy.

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Key Clinical Findings for Mounjaro

  1. SURMOUNT Trials: Participants taking the highest dose (15 mg) lost an average of 22.5% of their body weight over 72 weeks. 

  2. Appetite Suppression: Mounjaro slows gastric emptying and reduces hunger, leading to lower calorie intake. 

  3.  Metabolic Benefits: Beyond weight loss, it improves insulin sensitivity and cardiovascular health.

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How Does Mounjaro Work for Weight Loss?

1. Reduces Appetite: Acts on brain receptors to decrease hunger signals.

2. Slows Digestion: Keeps food in the stomach longer, promoting satiety.

3. Enhances Insulin Function: Helps regulate blood sugar, reducing fat storage.

Who Can Use Mounjaro for Weight Loss?

The FDA has approved Mounjaro for: 

  • Adults with obesity (BMI ≥ 30) 

  • Overweight individuals (BMI ≥ 27) with weight-related conditions (e.g, hypertension, diabetes)

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Side Effects & Considerations of Mounjaro

Common side effects include: 

  •  Nausea 

  •  Diarrhea 

  • Constipation 

  •  Mild hypoglycemia (in diabetics) 


Patients should consult their doctor before use, especially those with a history of pancreatitis or thyroid tumors. 


Mounjaro’s FDA approval for weight loss represents a major milestone in obesity treatment. With its unprecedented efficacy, it offers a powerful tool for sustainable weight management. However, it should be combined with lifestyle changes, healthy eating and exercise, for optimal results. 

As research continues, Mounjaro could redefine the future of medical weight loss solutions, providing hope for millions worldwide.

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